section 23.9
The Human Genome Project
541
13
l- BRCA2
Breast cancer
t
RB1
Retinoblastom a
L ATP7B
W ilson disease
14
PS1(AD3)
Alzheim er's
■
disease
15
. UBE3A
Angel m an
svndrom c
FBN1
M arfan syndrom e
16
U r-m r
I B
h a m ilia l M e d ite r -
ra n e a n fever
Polycystic
kidney disease
L Crobns disease
17
J-P 5 3
Si
liim or-
suppressor
protein
BRCA1
Breast cancc
18
r
19
NPC1
N iem ann-Pick
disease
“ DPC4 <
Sm ad4 »
Pancreatic cancer
1
j- APOE
1
Atheroscl
DM
u
M \otonic
P
a^rph.
20
21
22
1
ADA1
Severe com bined
2
p S0D1
A m yotrophic
J
J
im m uno-
deficiency
|H
lateral sclerosis
^
APS1
A utoim m une
|x>lyglandular
SMidmmc
3
BCR
Chronic myeloid
leukem ia
X
:
—
DM0
D uchenne
m uscular
3
dystrophy
ATP7A
P U M enkes
W
syndrom e
Y
7 1
i
SFY iTDf l
T estis-
determ ining
factor
FMR1
fragile \
. syndrom e
FIGURE 23-17 (
Continued
)
